Lecture topic: Road to Nobel Prize

Name of expert: Sir. Richard J. Roberts

Date: 2019-06-27

Time: 15:00

Location: Small Hall

Speaker introduction: Richard John Roberts (Richard John Roberts), Nobel Prize, American Academy of Academic Achievement Golden Disk Award, Sheffield University Council Award, Ross University Faye Robina Award, Royal Society Gabor Medal, Boston Legendary Leadership Award, the Hans Krebs Medal of the European Federation of Biochemical Societies (FEBS), and the winner of the Indian Diruba Ambani Lifetime Achievement Award. British, a well-known biochemistry and molecular biologist, received a Ph.D. in organic chemistry from the University of Sheffield in the United Kingdom in 1968. He has served as a researcher at Harvard University, an assistant to the research director of Cold Spring Harbor Laboratory, and a chief scientist at the New England Biological Laboratory. He mainly engaged in the study of eukaryotic gene structure and mRNA splicing mechanism. When studying the structure of eukaryotes, Roberts and Sharp discovered that the break gene is composed of the exons of the coding sequence and the introns of the non-coding sequence. Because of the "unique discovery of the break gene", Roberts and Sharp obtained the 1993 Nobel Prize in Physiology or Medicine. The discovery of broken genes has given people a deeper understanding of the gene structure of eukaryotes, changed the evolutionary theory of genes, and made people have a deeper understanding of the pathogenesis of certain diseases. Sir Roberts has published more than 260 papers in internationally renowned journals such as Science, Nature, PNAS, Nucl Acids Res, J Biol Chem, and participated in the compilation of more than 40 textbooks.

Main content: In this speech, Roberts will briefly describe how he became interested in science and how he almost became a professional billiard player. With his early interest in chemistry and the pursuit of a PhD in chemistry, he became fascinated by biology and read a book "The Line of Life" by John Kendrew, which made him a molecular biology Family. Roberts will describe the research that discovered RNA splicing, which turned out to be a temporary transfer of his real interest in DNA restriction and modification and bioinformatics. With a keen interest in DNA sequencing, Roberts began to use computers extensively and became a pioneer in what is now called bioinformatics. There have been many discoveries in the RM field, including some recent exciting discoveries about bacterial methyl bodies.

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