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朱海涛
发布日期:2021-12-27  浏览:

  朱海涛,男,1984年12月,医学博士,博士生导师,副主任医师/副教授。江苏大学影像学与人工智能研究院常务副院长;江苏大学医学影像系常务副主任,江苏大学附属医院影像科副主任兼医学影像实验室主任;江苏省科技智库杰出青年,江苏省“333”三层次人才,江苏省六大高峰人才,江苏省医学会优秀青年医师,江苏省青年医学重点人才,镇江市“169”科技骨干,镇江市优秀青年医师,江苏大学“新长征突击手”。在胰腺癌的影像诊断及分子影像现象方面有较多的积累,主要集中在:(1)在胰腺癌的弥散成像,灌注成像及利用IVIM等新技术评估肿瘤组织的纤维化程度等方面做了较多的工作;(2)通过设计新型的分子探针用于胰腺癌的超早期多模态成像。主持国家自然基金项目2项、江苏省社会发展面上项目1项,中华国际医学交流基金会项目1项,江苏省高校自然基金1项、镇江市社会发展项目1项;参与国家自然基金3项、江苏省社会发展项目2项。研究成果发表学术论文30余篇,其中以第一作者和通讯作者身份发表SCI论文10篇,I区TOP期刊4篇,影响因子大于10分的5篇;发表中华级论文5篇;申请专利3项;参编英文专著3部、人民卫生出版社专著1部。一篇研究成果入围2021年《全球铁死亡研究十大进展》;一篇研究成果入选2021年度中国影像医学领域高价值论文(排名37);先后获得江苏省医学科技进步二等奖和三等奖1项,镇江市科技进步二等奖和三等奖各1项。目前是中国医师协会放射学分会人工智能学组委员,江苏省医师协会放射学分会心血管学组副组长,江苏省放射学会分子影像学组委员、江苏省生物医学工程影像专委会委员,江苏省放射学会腹部学组秘书,江苏省放射学会青年委员会委员,江苏省医师学会青年委员会委员,江苏省免疫学会青年委员会委员。

1.受教育经历
2016/09-2020/08  南京大学,临床医学院,博士
2010/09-2013/07  江苏大学,临床医学院,硕 士
2003/09-2008/07  江苏大学,临床医学院,学士

2.研究工作经历
2016/04-2016/09  芬兰Turku大学附属医学,核医学中心,访问学者
2014/02-2014/05  德国汉诺威医学院,肿瘤研究中心,访问学者
2013/07-至今    江苏大学附属医院,影像科, 主治医师、硕导
2008/09-2013/06  南通大学附属第三人民医院,影像科,医师

3.近5年承担科研项目

4. 研究成果
一、近五年期刊论文
(1) Xuelian Chen, Lirong Zhang, Yujie Jiang, Lian Song, Yanfang Liu, Fang Cheng, Xin Fan, Xiongfeng Cao, Aihua Gong, Dongqing Wang, Haitao Zhu(通讯作者). Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis. Journal of Experimental & Clinical Cancer Research. 2018. 37: 77 (IF=6.217)
(2) Xuelian Chen, Fang Cheng, Yanfang Liu, Lirong Zhang, Lian Song, Xiaojie Cai, Tao You, Xin Fan, Dongqing Wang, Aihua Gong, Haitao Zhu(通讯作者). Toll-like receptor 2 and Toll-like receptor 4 exhibit distinct regulation of cancer cell stemness mediated by cell death-induced high-mobility group box 1. EBioMedicine. 2019, (40): 135-150. (IF=6.68,TOP, I区,配发述评,封面文章)
(3) Kang Wang, Zhengyang Zhang, Ming Wang, Xiongfeng Cao, Jianchen Qi, Dongqing Wang, Aihua Gong, Haitao Zhu(通讯作者).. Role of GRP78 inhibiting artesunate-induced ferroptosis in KRAS mutant pancreatic cancer cells. Drug Design, Development and Therapy,2019(13):2135-2144 (IF=3.208)
(4) Lirong Zhang, Hui Shi, Hongbo Chen, Aihua Gong, Yanfang Liu, Lian Song, Xuewen Xu, Tao You, Xin Fan,Dongqing Wang, Fang Cheng, Haitao Zhu(通讯作者). Dedifferentiation process driven by radiotherapyinduced HMGB1/TLR2/YAP/HIF-1α signaling enhances pancreatic cancer stemness. Cell Death and Disease. 2019, 10:724.
(5) Haitao Zhu, Xiongfeng Cao, Xiaojie Cai, Ying Tian, Dongqing Wang, Jianchen Qi, Zhaogang Teng, Guangming Lu, Qianqian Ni, Shouju Wang, Longjiang Zhang. Pifthrin-μ incorporated in gold nanoparticle amplifes pro-apoptotic unfolded protein response cascades to potentiate synergistic glioblastoma therapy. Biomaterials, 2020 (232): 119677.(IF=10.27,TOP, I区)
(6) Dandan Su, Hsiang-I Tsai, Zhanxue Xu, Fuxia Yan, Yingyi Wu, Youmei Xiao, Xiaoyan Liu, Yanping Wu, Sepideh Parvanian, Wangshu Zhu, John E. Eriksson, Dongqing Wang, Haitao Zhu(通讯作者), Hongbo Chen, Fang Cheng. Exosomal PD-L1 functions as animmunosuppressant to promote wound healing. Journal of Extracellular Vesicles, 2020, (9):1709262. (IF=14.9,TOP, I区)
(7) Kang Wang, Zhengyang Zhang, Hsiang-i Tsai, Yanfang Liu, Jie Gao, Ming Wang, Lian Song, Xiongfeng Cao, Zhanxue Xu, Hongbo Chen, Aihua Gong, Dongqing Wang, Fang Cheng, Haitao Zhu(通讯作者). Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells. Cell Death & Differentiation, 2021, (IF=10.7,TOP, I区)
(8) Haitao Zhu, Jianchen Qi,,Joseph Schoepf, Rock H. Savage, Chunxiang Tang,  Mengjie Lu,  Changsheng Zhou,  Guangming Lu,  Dongqing Wang, Longjiang Zhang, Prevalence and Associated Risk Factors of Pulmonary Embolism in Children and Young Adults With Nephrotic Syndrome A Chinese Large Cohort Study. Journal of thoracic imaging.2021, 36(5):326-332.
(9) Sai Liu, Xiongfeng Cao, Dongqing Wang, Haitao Zhu(通讯作者). Iron metabolism: State of the art in hypoxic cancer cell biology. Archives of Biochemistry and Biophysics, 2022, 723:109199.
(10) Yaxin Guo, Hsiang-i Tsai, Lirong Zhang, Haitao Zhu(通讯作者). Mitochondrial DNA on Tumor-Associated Macrophages Polarization and Immunity. Cancers, 2022, 14, 1452.
(11) Qiwei Wu, Hsiang-i Tsai , Haitao Zhu(通讯作者), Dongqing Wang. The Entanglement between Mitochondrial DNA and Tumor Metastasis. Cancers, 2022, 14, 1862.
(12) Qiwei Wu, Lian Song, Yaxin Guo, Sai Liu, Wenyao Wang, Huli Liu, Aihua Gong, Xiang Liao, Haitao Zhu, Dongqing Wang. Activated Stellate Cell Paracrine HGF Exacerbated Pancreatic Cancer Cell Ferroptosis Resistance. Oxidative Medicine and Cellular Longevity, 2022, 2985249
(13) Xin Wang, Mengqi Liu, Yue Chu, Yanfang Liu, Xiongfeng Cao, Han Zhang, Yao Huang, Aihua Gong, Xiang Liao, Dongqing Wang, Haitao Zhu. O-GlcNAcylation of ZEB1 facilitated mesenchymal pancreatic cancer cell ferroptosis. International Journal of Biological Sciences.2022; 18(10): 4135-4150. (IF=10.2)
(14) Yinhui Hang, Yanfang Liu, Zhaogang Teng, Xiongfeng Cao, Haitao Zhu(通讯作者). Mesoporous nanodrug delivery system: a powerful tool for a new paradigm of remodeling of the tumor microenvironment. Journal of Nanobiotechnology. (2023) 21:101. (IF=10.7,I区)

二、专著
(1) Haitao Zhu, Dongqing Wang, Yanfang Liu, Zhaoliang Su, Zhijian Zhang, Ruigen Yin, Liang Zhao, Yan Zhu, Juan Hong, Jie Zhang. Multi-role of cancer stem cells in Children Acute Lymphoblastic Leukemia. Novel Aspects in Acute Lymphoblastic Leukemia, Intech Open Acess  publisher, 2012.
(2) Zhaoliang Su, Haitao Zhu, Yanfang  Liu, Huaxi Wu. Multidrug Resistance Mechanism of Acute Lymphoblastic Leukemia, Clinical Epidemiology of ALL-From the molecules to the clinic, Intech Open Acess publisher, 2011.
(3)Xiaoxiao Yang, Xuewen Xu, Yanfang Liu, Aihua Gong, Dongqing Wang, Xiang Liao and Haitao Zhu. Advances in Acute MyeloidLeukemia Stem Cells. Advances in Hematologic Malignancies. Intech Open Acess publisher, 2019.
(4)Xiaojie Cai, Jie Gao, Yanfang Liu, Ming Wang, Qiulian Ma, Aihua Gong, Dongqing Wang, Haitao Zhu.Advance in Pancreatic Cancer Diagnosis and Therapy. Pancreatic Cancer. Intech Open Acess publisher, 2021.

三、专利
(1)陈秋云,朱海涛。检测的荧光核酸银制备方法及其在肿瘤干细胞检测中的应用,发明专利。
(2)张子宁,蔡湘仪,曹雄峰,朱海涛,浦旭峰,张恒。一种靶向纳米分子探针及其在制备肿瘤治疗药物中的应用;发明专利。
(3)朱海涛,吉江红,蔡湘仪,王冬青。一种改善胰腺癌吉西他滨耐药分子探针的制备及其应用;发明专利。

四、科技获奖
(1) 王冬青,曾蒙苏,陈秋云,张礼荣,朱海涛。肿瘤缺氧微环境及其因子HIF-1a在胰腺癌发生发展中的基础及临床应用研究,2018,江苏省医学科技进步奖,三等奖。
(2)王冬青,王中秋,朱海涛,杜凤移,张礼荣,宋廉,张正阳。分子诊疗一体化策略在胰腺癌放疗增敏中应用研究,2022,江苏省医学科技进步奖,二等奖。
(3)王冬青,朱海涛,刘春雨。基于能量CT的慢性代谢性疾病患者冠状动脉钙化负荷新技术建立及其应用,2023,江苏省卫生健康委新技术引进奖,二等奖。


 
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