Yu Tian
Assistant Researcher, engaged in research on cardiac and neural immunity.
Email: 1000006331@ujs.edu.cn
Educational Background
2011.9-2016.6: Bachelor's degree from Qinghai University, School of Medicine.
2016.9-2022.9: Master's/Ph.D. from Jiangsu University, School of Medicine.
Work Experience
2022.12-present: Jiangsu University, School of Life Sciences (International Genomics Research Center).
Ongoing Research Project
Evaluation of the Impact of HMGB1 A Box on Several Human Immune Cells, April 2023 - April 2024, 500,000 RMB
Published Articles (#Co-first Author)
1.Tian Yu, Gong Xiangmei,Qin Demeng et al. S1PR1-dependent migration of ILC3s from intestinal tissue to the heart in a mouse model of viral myocarditis. J Leukoc Biol, 2023, DOI: 10.1093/jleuko/qiad048.
2.Tian Yu, Cao Yuwen,Chen Rong et al. HMGB1 A box protects neurons by potently inhibiting both microglia and T cell-mediated inflammation in a mouse Parkinson's disease model.[J] .Clin Sci (Lond), 2020, DOI: 10.1042/CS20200553.
3.Tian Yu, Chen Rong,Su Zhaoliang,HMGB1 is a Potential and Challenging Therapeutic Target for Parkinson's Disease.[J] .Cell Mol Neurobiol, 2021, DOI: 10.1007/s10571-021-01170-8.
4.Zhou Lining, Tian Yu#, Guo Fang et al. LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development. [J]. Cancer Immunol Immunother, 2020, DOI: 10.1007/s00262-020-02511-0.
5.Che Yang, Tian Yu#, Chen Rong et al. IL-22 ameliorated cardiomyocyte apoptosis in cardiac ischemia/reperfusion injury by blocking mitochondrial membrane potential decrease, inhibiting ROS and cytochrome C.[J]. Biochim Biophys Acta Mol Basis Dis, 2021, DOI: 10.1016/j.bbadis.2021.166171.
6.Cao Yuwen, Tian Yu#, Liu Yueqin et al. Reg3β: A Potential Therapeutic Target for Tissue Injury and Inflammation-Associated Disorders. [J]. Int Rev Immunol, 2021, DOI: 10.1080/08830185.2020.1869731.
7.Chen Rong., Cao Yuwen., Tian Yu., Gu Yufeng., Lu Hongxiang., Zhang Shiqing., Xu Huaxi., Su Zhaoliang.(2020). PGE2 ameliorated viral myocarditis development and promoted IL-10-producing regulatory B cell expansion via MAPKs/AKT-AP1 axis or AhR signaling. Cell Immunol, 347(undefined), 104025. doi:10.1016/j.cellimm. 2019.104025
8.Lu Hongxiang., Chen Rong., Barnie Prince Amoah., Tian Yu., Zhang Shiqing., Xu Huaxi., Chakrabarti Subrata., Su Zhaoliang.(2020). Fibroblast transdifferentiation promotes conversion of M1 macrophages and replenishment of cardiac resident macrophages following cardiac injury in mice. Eur J Immunol, 50(6), 795-808. doi:10.1002/eji.201948414
9.Huang Lan., Wan Jie., Wu Yinqiu., Tian Yu., Yao Yizheng., Yao Shun., Ji Xiaoyun., Wang Shengjun., Su Zhaoliang., Xu Huaxi.(2021). Challenges in adeno-associated virus-based treatment of central nervous system diseases through systemic injection. Life Sci, 270(undefined), 119142. doi:10.1016/j.lfs.2021.119142
10.Wan Jie., Wu Yinqiu., Huang Lan., Tian Yu., Ji Xiaoyun., Abdelaziz Mohamed Hamed., Cai Wei., Dineshkumar Kesavan., Lei Yuqing., Yao Shun., Sun Caixia., Su Zhaoliang., Wang Shengjun., Xu Huaxi.(2021). ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8 T cells. Cancer Lett, 502(undefined), 34-43. doi:10.1016/j.canlet.2021.01.002
11.Li Jiali., Xia Lin., Liu Fang., Tian Yu., Chen Rong., Su Zhaoliang.(2021). lncRNA187415.1 silence in BCAMs ameliorated breast cancer progression by blocking C/EBPβ-lncRNA187415.1-CISH axis and reversing pro-tumor characteristic of BCAMs. Clin Transl Med, 11(5), e407. doi:10.1002/ctm2.407
12.Chen Wenli., Yao Shun., Wan Jie., Tian Yu., Huang Lan., Wang Shanshan., Akter Farhana., Wu Yinqiu., Yao Yizheng., Zhang Xiaochun.(2021). BBB-crossing adeno-associated virus vector: An excellent gene delivery tool for CNS disease treatment. J Control Release, 333(undefined), 129-138. doi:10.1016/j.jconrel. 2021.03.029
13.Chen Rong., Liu Fang., Xia Lin., Che Nan., Tian Yu., Cao Yuwen., Zhang Shiqing., Xu Huaxi., Su Zhaoliang.(2021). B10 cells decrease fibrosis progression following cardiac injury partially by IL-10 production and regulating hyaluronan secretion. J Leukoc Biol, undefined(undefined), undefined. doi:10.1002/JLB.3A0121-003RR
