
Lin Xia, Research Assistant, Master Supervisor
Academic background
Postdoctor, International Genome Center, Jiangsu University, 2019-Present;
Research Assistant, Department of Laboratory Medicine, Affiliated Hospital of Jiangsu University, 2016-Present
Research fields
Immunometabolism; Cardiac injury and remodeling
Key scientific research projects
1. The mechanisms of 5’-AMP reprogramming cardiac infiltrating macrophages to resolve inflammation in mice with experimental autoimmune myocarditis. Agency: National Natural Science Foundation of China (Grant No. 81902136), Period: Jan 1, 2020-Dec 31, 2022
2. The mechanisms of 5’-AMP-ALOX15 regulating Mφ to resolve inflammation in mice with myocarditis. Agency: Chinese Postdoctoral Science Foundation (Grant No. 2019M660106), Period: Nov 1, 2019-Oct 31, 2021,
3. The mechanisms of extracellular purine nucleotides ameliorating LPS-induced acute kidney injury. Agency: Science and Technology Planning Social Development Project of Zhenjiang City (Grant No. SH2018027), Period: Jul 1, 2018- Jun 30, 2020.
Main achievements
1.Qin D, Zhang Y, Liu F, Xu X, Jiang H, Su Z, Xia L, Spatiotemporal development and regulatory mechanisms of cardiac resident macrophages: contribution in cardiac development and steady-state. Acta Physiol. 2024; Accepted
2.Zheng H, Cao P, Su Z, Xia L. Insights into the roles of IL-10-producing regulatory B cells in cardiovascular disorders: Recent advances and future perspectives. J Leukoc Biol. 2023; 114(4): 315-324.
3.Li J, Xia L, Liu F, Tian Y, Chen R, Su Z, lncRNA187415.1 silence in BCAMs ameliorated breast cancer progression by blocking C/EBPβ-lncRNA187415.1-CISH axis and reversing pro-tumor characteristic of BCAMs, Clin Transl Med. 2021; 11(5): e407.
4.Xia L, Wang Z, Zhang Y, Yang X, Zhan Y, Cheng R, Wang S, Zhang J, Reciprocal regulation of insulin and plasma 5’-AMP in glucose homeostasis in mice, J Endocrinol, 2015; 224(3): 225-34.