个人信息
陈坚，博士，博士生导师，教授
Email: jianchen (at) ujs.edu.cn
教育背景
2003.9-2007.7 浙江工业大学，学士
2007.9-2010.7 南京农业大学，硕士
2010.10-2014.10 意大利维罗纳大学，博士
工作经历
2015.1-2019.9 美国南卡罗莱纳大学，博士后
2020.4-现在 江苏大学，金山青年特聘教授，江苏大学特聘教授
荣誉称号
江苏特聘教授
学术兼职
Frontiers in Plant Science, Associate Editor.
Frontiers in Microbiology, Associate Editor.
Plant Physiology, Assistant Features Editor
Stress Biology, Guest Editor.
江苏省免疫学会青工委副主任委员
代表性论文论著（#共同第一作者，*通讯作者）:
2024
· Ikram AU#, Jing Y#, Chen H*, Chen J*. Two paths, one goal: mechanism of calcium homeostasis to balance plant growth and immunity. Sci China Life Sci. 2024 Nov 28.
· Xin K, Wu Y, Ikram AU, Jin Y, Liu S, Zhang Y, Chen J*. Salicylic acid cooperates with different small molecules to control biotic and abiotic stress responses. J Plant Physiol. 2024
· Ikram, AU#, Khan MSSS#, Islam F, Ahmed S, Ling T, Feng F, Sun Z*, Chen H*, and Chen J*. All roads lead to Rome: Pathways to engineering disease resistance in plants. Advanced Science. 2024. In press.
·Islam F, Khan MSS, Ahmed S, Ikram AI, Hannan F, Jan M, Sajid M, Shoaib AIZ, Liu S*, Chen J*. Dynamic interplay of silica-coated iron oxide nanocomposite on soil-plant system to mitigate Cd toxicity in rice, Journal of Cleaner Production. 2024. 471:143267
·Elsisi M#, Elshiekh M#, Sabry N#, Aziz M, Attia K, Islam F*, Chen J*, Abdelrahman M*. The genetic orchestra of salicylic acid in plant resilience to climate change induced abiotic stress: critical review. Stress Biol. 2024 Jun 17;4(1):31.
·Islam F, Khan MSS*, Ahmed S, Ikram AU, Hannan F, Jan M, Muhammad S, Chen J*. Transcriptomic reprogramming of rice cultivars in response to herbicide, salt and their combined stresses. Plant Stress. 2024 June. 12:100504.
·Sulaiman Ahmed#, Muhammad Saad Shoaib Khan#, Songlei Xue#, Faisal Islam, Aziz Ul Ikram, Muhammad Abdullah, Shan Liu*, Piengtawan Tappiban*, Jian Chen*. A comprehensive overview of omics-based approaches to enhance biotic and abiotic stress tolerance in sweet potato. Horticulture Research, 2024;, uhae014
·Fang Y, Chen J*. A Ying and Yang balance: Transcription factors OsNAC2 and OsEREBP1 synergistically regulate plant immunity. Plant Physiol. 2024 Jan 19:kiae031.
·Jing Yanping , Zhao Fugeng , Lai Ke , Sun Fei , Sun Chenjie , Zou Xingyue , Xu Min , Fu Aigen , Sharifi Rouhallah , Chen Jian*, Zheng Xiaojiang*, Luan Sheng*. Plant elicitor Peptides regulate root hair development in Arabidopsis. Front Plant Sci. 2024.
·Liu S#, Islam F#, Chen J, Sun Z*, Chen J*. Attention, neighbors: methyl salicylate mediates plant airborne defence. Plant Commun. 2024 Jan 8;5(1):100746.
2023
·Jing Y#, Zheng X#*, Sharifi R, Chen J*. Plant elicitor peptide induces endocytosis of plasma membrane proteins in Arabidopsis. Front Plant Sci. 2023 Dec 22;14:1328250.
·Ikram AU#, Jing Y#, Chen H*, Chen J*. Bacteria deploy water channels to aid infection in plants. Trends Plant Sci. 2023 Dec 28:S1360-1385(23)00413-2.
·Islam F#, Liu S#, Chen H*, Chen J*. Reprogramming of hormone-mediated antiviral responses in plants by viruses: a molecular tug of war on the salicylic acid-mediated immunity. Mol Plant. 2023 Oct 2;16(10):1493-1495.
·Majeed A#, Kui L#, Dong Y*, Chen J*. Reference genome facilitates trait development for faba beans. Trends Genet. 2023 Oct;39(10):724-727
·Khan MSS#, Ahmed S#, Ikram AU#, Hannan F, Yasin MU, Wang J, Zhao B*, Islam F*, Chen J*. Phytomelatonin: A key regulator of redox and phytohormones signaling against biotic/abiotic stresses. Redox Biol. 2023 Aug;64:102805.
·Sharifi R, Chen J, Sun Z*, Chen J*. Conferring resistance to parasitic witchweed by shifting strigolactone biosynthesis. Trends Parasitol. 2023 Jul;39(7):496-498
·Chen J*, Chen J, Sun Z*. Staying vigilant: NLR monitors virus invasion. Trends Plant Sci. 2023 Jun;28(6):617-619.
·Fang Y, Chen J*. Changing the script: A Phytophthora sojae effector hijacks RNA-binding proteins to reprogram plant immunity. Plant Physiol. 2023 Feb 12;191(2):820-822.
·Islam F*, Khan MSS*, Ahmed S, Abdullah M, Hannan F, Chen J*. OsLPXC negatively regulates tolerance to cold stress via modulating oxidative stress, antioxidant defense and JA accumulation in rice. Free Radic Biol Med. 2023 Feb 10;199:2-16
2022
·Chen J*. Need help? Recently identified phosphorylation targets of MAP kinase 4 aid plant immunity. Plant Physiol. 2022 Oct 27;190(3):1556-1558.
·Chen R, He J, Su Z, Chen J*. A plant immune protein fights against cancer. Trends Biochem Sci. 2022 Dec;47(12):996-998.
·Kui L#, Majeed A#, Ahmed S, Khan MSS, Islam F, Chen J*, Dong Y*. Solanum tuberosum (potato). Trends Genet. 2022 Nov;38(11):1193-1195.
·Chen J*. Bringing it in: a transporter of extracellular amino acids for regulation of plant immunity. Plant Physiol. 2022 Aug 29;190(1):190-192.
·Ahmed S, Chen J*. Transcription factor OsNAC016: a convergent point of brassinosteroid and abscisic acid signaling in rice. Plant Physiol. 2022 Jun 27;189(3):1177-1179.
·Khan MSS#, Islam F#, Ye Y, Ashline M, Wang D, Zhao B, Fu ZQ*, Chen J*. The Interplay between Hydrogen Sulfide and Phytohormone Signaling Pathways under Challenging Environments. Int J Mol Sci. 2022, Apr 12;23(8):4272
·Khan MSS, Chen J*. Regulation of the interplay between reactive oxygen species and SUMOylation pathways: an essential role for SIZ1. Plant Physiol. 2022 Jun 1;189(2):454-456.
·Chen H#, Chen J#, Zhao Y, Liu F*, Fu ZQ*. Pseudomonas syringae pathovars. Trends Microbiol. 2022 Sep;30(9):912-913.
·Khan MSS#, Islam F#, Chen H, Chang M, Wang D, Liu F*, Fu ZQ*, Chen J*. Transcriptional Coactivators: Driving Force of Plant Immunity. Front Plant Sci. 2022 Jan 28;13:823937.
·Chen J#, Sharifi R#, Khan MSS#, Islam F, Bhat JA, Kui L*, Majeed A*. Wheat Microbiome: Structure, Dynamics, and Role in Improving Performance Under Stress Environments. Front Microbiol. 2022 Jan 13;12:821546.
·Chen J, Chen H, Liu F*, Fu ZQ*. A war on the cell wall. Mol Plant. 2022 Feb 7;15(2):219-221.
·Chen J, Sharifi R*, Ryu CM*. Turning a bacterial gaseous virulence trigger off. Trends Plant Sci. 2022 Jan;27(1):4-6.
2021
·Chen J, Daowen Wang*, Fu ZQ*. Degradation without Ubiquitination: New Function of a Parasite Effector. Trends Parasitol. 2021 Dec;37(12):1024-1026.
·Chen J, Zhou H, Xie Y*. SnRK2.6 phosphorylation/persulfidation: where ABA and H2S signaling meet, Trends Plant Sci. 2021 Dec;26(12):1207-1209.
·Kong M, Sheng T, Liang J, Ali Q, Gu Q, Wu H, Chen J*, Liu J*, and Gao X*. Melatonin and Its Homologs Induce Immune Responses via Receptors trP47363-trP13076 in Nicotiana benthamiana. Front Plant Sci. 2021 Jun 30;12:691835.
·Chen J#, Li M#, Liu L, Chen G*, Fu ZQ*. ZAR1 Resistosome and Helper NLRs: Bringing in Calcium and Inducing Cell Death. Mol Plant. 2021 Aug 2;14(8):1234-1236.
·Wang X#, Chen J#, Liu N*, Fu ZQ*. Dual Functions of a Stable Peptide against Citrus Huanglongbing Disease. Trends Plant Sci. 2021 Jul;26(7):668-670.
·Chen J#*, Zhang J#, Kong M#, Freeman A, Chen H*, Liu F*. More stories to tell: NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1, a salicylic acid receptor. Plant Cell Environ. 2021 Feb;44(6):1716-1727.
2009-2020
·Chen J, Clinton M, Qi G, Wang D, Liu F*, and Fu ZQ*. Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense. J Exp Bot. 2020 Aug 17;71(17):5256-5268.
·Chen J, Mohan R, Zhang Y, Li M, Chen H, Palmer IA, Chang M, Qi G, Spoel SH, Mengiste T, Wang D, Liu F*, Fu ZQ*. NPR1 Promotes Its Own and Target Gene Expression in Plant Defense by Recruiting CDK8. Plant Physiol. 2019 Sep;181(1):289-304.
·Qi G#, Chen J#, Chang M#, Chen H, Hall K, Korin J, Liu F*, Wang D*, Fu ZQ*. Pandemonium Breaks Out: Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens. Mol Plant. 2018 Dec 3;11(12):1427-1439.
·Hussain J#, Chen J#, Locato V#, Sabetta W#, Behera S, Cimini S, Griggio F, Martínez-Jaime S, Graf A, Bouneb M, Pachaiappan R, Fincato P, Blanco E, Costa A, De Gara L, Bellin D*, de Pinto MC, Vandelle E*. Constitutive cyclic GMP accumulation in Arabidopsis thaliana compromises systemic acquired resistance induced by an avirulent pathogen by modulating local signals. Sci Rep. 2016 Nov 4;6:36423.
·Chen J#, Vandelle E#, Bellin D, Delledonne M*. Detection and function of nitric oxide during the hypersensitive response in Arabidopsis thaliana: where there's a will there's a way. Nitric Oxide. 2014 Dec 1;43:81-8.
·陈坚, 耿贝贝, 沈文飚, 黄丽琴 (2009) 一氧化碳在植物体内的信号转导作用。 生命的化学 29: 283-286
Book Chapter:
·Chen J, Bellin D, Vandelle E. Measurement of Cyclic GMP During Plant Hypersensitive Disease Resistance Response. Methods Mol Biol. 2018;1743:143-151.
参与发表的文章：
·Kui L, Majeed A, Wang X, Yang Z, Chen J, He L, Di Y, Li X, Qian Z, Jiao Y, Wang G, Liu L, Xu R, Gu S, Yang Q, Chen S, Lou H, Meng Y, Xie L, Xu F, Shen Q, Singh A, Gruber K, Pan Y, Hao T, Dong Y, Li F. A chromosome-level genome assembly for Erianthus fulvus provides insights into its biofuel potential and facilitates breeding for improvement of sugarcane. Plant Commun. 2023 Jul 10;4(4):100562.
·Qi G, Chen H, Wang D, Zheng H, Tang X, Guo Z, Cheng J, Chen J, Wang Y, Bai MY, Liu F, Wang D, Fu ZQ. The BZR1-EDS1 module regulates plant growth-defense coordination. Mol Plant. 2021 Dec 6;14(12):2072-2087.
·Zhang R, Chen J, Wang D, Fu ZQ. Hijacking of host mitochondria by Toxoplasma gondii and SARS-CoV-2. Trends Parasitol. 2022 Feb 8:S1471-4922(22)00032-0
·Kui L, Chen B, Chen J, Sharifi R, Dong Y, Zhang Z, Miao J. A Comparative Analysis on the Structure and Function of the Panax notoginseng Rhizosphere Microbiome. Front Microbiol. 2021 Jun 9;12:673512.
·Palmer IA, Chen H, Chen J, Chang M, Li M, Liu F, Fu ZQ. Novel Salicylic Acid Analogs Induce a Potent Defense Response in Arabidopsis. Int J Mol Sci. 2019 Jul 8;20(13).
·Chang M, Zhao J, Chen H, Li G, Chen J, Li M, Palmer IA, Song J, Alfano JR, Liu F, Fu ZQ. PBS3 Protects EDS1 from Proteasome-Mediated Degradation in Plant Immunity. Mol Plant. 2019 Feb 11. (IF=12.08)·Li M, Chen H, Chen J, Chang M, Palmer IA, Gassmann W, Liu F, Fu ZQ. TCP Transcription Factors Interact With NPR1 and Contribute Redundantly to Systemic Acquired Resistance. Front Plant Sci. 2018 Aug 14;9:1153.
·Chen H, Palmer IA, Chen J, Chang M, Thompson SL, Liu F, Fu ZQ. Specific and Accurate Detection of the Citrus Greening Pathogen Candidatus liberibacter spp. Using Conventional PCR on Citrus Leaf Tissue Samples. J Vis Exp. 2018 Jun 29;(136).
·Chen H, Chen J, Li M, Chang M, Xu KM, Shang ZH, Zhao Y, Palmer I, Zhang YQ, McGrill J, Alfano JR, Nishimura MT, Liu FQ, and Fu ZQ. A Bacterial Type III Effector Targets the Master Regulator of Salicylic Acid Signaling NPR1 to Subvert Plant Immunity. Cell Host Microbe. 2017 Dec 13;22(6):777-788 (F1000Prime)
·Kumar N, Astegno A, Chen J, Giorgetti A, Dominici P. Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity. Int. J. Mol. Sci. 2016, 17(5), 640
·Chen XY, Ding X, Xu S, Wang R, Xuan W, Cao ZY, Chen J, Wu HH, Ye MB, Shen WB (2009) Endogenous hydrogen peroxide plays a positive role in the upregulation of heme oxygenase and acclimation to oxidative stress in wheat seedling leaves. J Integr Plant Biol 51: 951–960
科研项目
·科技部外国专家项目，WGXZ2023022L，2023.1-2024.12，项目负责人，20万元
·科技部外国专家项目，WGXZ2023024L，2023.1-2024.12，项目负责人，20万元
·江苏省自然科学基金面上项目，水杨酸受体 NPR1/3/4 与丁香假单胞菌效应因子 HopAO1 的互作机制研究，BK20211319，2021.7-2024.7，主持
·国家自然科学基金青年项目，丁香假单胞菌效应蛋白HopAO1与拟南芥免疫信号蛋白互作机制研究32000201，2021.1-2023.12，24万元，主持
·江苏大学高级人才启动基金，20JDG34, 40万元，主持
·南卡罗莱纳大学博士后基金Aspire I track II B，Unravel the function of NPR1 interacting La-related proteins in plant defense response, 13010-17-44719，2017.7-2018.9，0.5万美元，主持。
·国家自然科学基金青年项目，新型植物免疫复合体PBS3-EDS1促进植物抗病性机制研究，31701863，2018.1-2020.12，25万元，参与, 第二，已结题
·美国国家自然科学基金，Targeting of salicylic acid-activated NPR1 by a bacterial type III effector，1758994，2018.8.1-2021.7.31，49.3万美元，参与，第三，已结题
·美国国家自然科学基金，Salicylic acid signaling in plant pathogen interactions，13010-FC43，2015.8.1-2016.7.3，14.8万美元，参与，第二
·国家自然科学基金面上项目，水稻白叶枯病菌中一个新致病因子受寄主诱导及其调控致病性的机制研究，31571974，2016.1-2019.12，65万元，参与，第三
研究方向：
1 水杨酸信号通路在植物免疫中的作用
2 丁香假单胞菌三型效应因子与植物免疫蛋白的互作机制
3 小肽在调节植物生长与免疫中的作用及机制
本课题组长期招聘博士后，助理研究员，副研究员，同时欢迎硕士生及博士生的加入
