I. Personal information
Title: Research Assistant
Highest academic degree: Ph.D
E-mail: xialinfzdx@126.com
II. Academic background
Postdoctor, International Genome Center, Jiangsu University, 2019-Present;
Research Assistant, Department of Laboratory Medicine, Affiliated Hospital of Jiangsu University, 2016-Present
III. Research fields
Immune metabolism in inflammation; Cardiac injury and functional remodeling; Autoimmune disease
IV. Key scientific research projects
1.The mechanisms of 5’-AMP reprogramming cardiac infiltrating macrophages to resolve inflammation in mice with experimental autoimmune myocarditis. Agency: National Natural Science Foundation of China (Grant No. 81902136), Period: Jan 1, 2020-Dec 31, 2022
2.The mechanisms of 5’-AMP-ALOX15 regulating Mφ to resolve inflammation in mice with myocarditis. Agency: Chinese Postdoctoral Science Foundation (Grant No. 2019M660106), Period: Oct 1, 2019-Sep 31, 2021,
3.The mechanisms of extracellular purine nucleotides ameliorating LPS-induced acute kidney injury. Agency: Science and Technology Planning Social Development Project of Zhenjiang City (Grant No. SH2018027), Period: Jul 1, 2018- Jun 30, 2020.
V. Main achievements
1.Xia L, Wang Z, Zhang Y, Yang X, Zhan Y, Cheng R, Wang S, Zhang J. Reciprocal regulation of insulin and plasma 5’-AMP in glucose homeostasis in mice. Journal of Endocrinology, 2015; 224(3):225-34.
2.Xia L, Ma S, Zhang Y, Wang T, Zhou M, Wang Z, Zhang J. Daily variation in global and local DNA methylation in mouse livers. PLoS One, 2015; 17;10(2): e0118101.
3.Dong F, Xia L, Lu R, Zhao X, Zhang Y, Zhang Y, Huang X. The malS-5’UTR weakens the ability of Salmonella enterica serovar Typhi to survive in macrophages by increasing intracellular ATP levels. Microbial Pathogenesis, 2018; 115:321-331.