Personal Information
Name: Haitao Zhu
Gender: Male
Education:
September,2003-July,2008 Jiangsu University ;Clinic;B.E.
September,2010-July, 2013 Jiangsu University; Major: Radiology; M.S.
September,2017-July,2020 Nanjing University; Major: Radiology; Ph.D.
Professional experience:
September, 2008- September, 2010 The third people’s hospital of Wuxi; Doctor
September, 2013- The Affiliated hospital of Jiangsu University; Doctor
Work Address:
Department of Radiology, The Affiliated hospital of Jiangsu University,NO.438 Jiefang Road, Zhenjiang, Jiangsu province 212013, PRC
Tel:+86-18796001735
Email:zhht25@163.com
Memberships:
Board Member of Jiangsu Association of Immunology
Board Member of Zhenjiang Association of Radiology
Meeting:
70th Japanese Cancer Annual Meeting in Nagoya.(2011)
17thCCR Annual Meeting in Henan.(2011)
16thCCR Annual Meeting in Jinan.(2010)
Research Skills:
1.Diagnose diseases with MRI and CT: Skilled in diagnosing various diseases with MRI or CT,especially in tumor diseases.
2.Animal experiments: Isolate fresh bone marrow cells and liver cell from mice and rats.Prepare tumor models in nude mice . Tail vein injection of virus and plasmid
3.Cell and Tissue culture: Skilled in culturing various tumor cell lines, blood cells, fetal liver cell, bone marrow stromal cells, adipose cells. Transfer target genes or siRNA into the cell by transfection reagent or viral vecor.
4.Immunocytochemical techniques: Histology on cell and tissue section; ELISA. Viral techniques: Make and produce adenovirus and lentivirus.
5.Molecular biology techniques: Design and make vectors, cDNA cloning and characterization,prepare DNA and RAN samples and characterize them, PCR, RT-PCR, quantitative Real-Time PCR, Site-directed mutagenosis.
Research projects:
1. The mechanism of pancreatic cancer stem cell mediated lymph node metastasis and establishes novel molecular probes; Jiangsu National Natural Science Foundation;2011-2014
Selected Publications
（1）Xuelian Chen, Lirong Zhang, Yujie Jiang, Lian Song, Yanfang Liu, Fang Cheng, Xin Fan, Xiongfeng Cao, Aihua Gong, Dongqing Wang, Haitao Zhu(Correspondence author). Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis. J Exp Clin Canc Res
（2）Lirong Zhang, Dongqing Wang, Yanfang Li, Xiaodong Xie, Yingying Wu, Zhaoliang Su, Haitao Zhu(Correspondence author). CCL21/CCR7 overexpression in CD133+ pancreatic cancer stem-like cells promoted lymph node metastasis via EMT and Erk/NF-κB pathway. Plos One
（3）Zhu H, Wang D, Zhang L, Xie X , Wu Y ,Liu Y, Zhou Y, Yin R, Zhang Z, Shao G, Su Z. Up-regulation of autophagy by Hypoxia-inducible factor-1 alpha promotes EMT and metastasis ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia, Oncol Rep., 2014 Jul 2. doi: 10.3892.
（4）Zhu H, Wang D*, Liu Y, Su Z, Zhang L, Chen F, Zhou Y, Wu Y, Yu M, Zhang Z, Shao G. Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells, Cancer Cell Int, 13(1):119, 2013.
（5）Wang D, Zhu H(Co-first author)，Liu Y, Liu Q, Xie X, Zhou Y, Zhang L, Zhu Y, Zhang Z, Su Z*. The Low Chamber Pancreatic Cancer Cells had Stem-Like Characteristics in Modified Transwell System: Is a Novel Method to Identify and Enrich Cancer Stem-Like Cells? BioMed Research International. http://dx.doi.org/10.1155/2014/760303.
（6）Xinxin Xu, Haitao Zhu(Co-first author), Ting Wang, Yingkun Sun, Huiling Shen, Wenlin Xu, Huaxi Xu, Zhaoliang Su. Exogenous High Mobility Group Box-1 Inhibits Apoptosis and Promotes the Proliferation of Lewis Cells via RAGE/TLR4-Dependent Signal Pathways. Scand J Immunol, doi: 10.1111/sji.12174. 2014.
（7）Haitao Zhu, Xiongfeng Cao, Xiaojie Cai, Ying Tian, Dongqing Wang, Jianchen Qi, Zhaogang Teng, Guangming Lu, Qianqian Ni, Shouju Wang, Longjiang Zhang. Pifthrin-μ incorporated in gold nanoparticle amplifes pro-apoptotic unfolded protein response cascades to potentiate synergistic glioblastoma therapy. Biomaterials, 2020 (232): 119677.
（8）Dandan Su, Hsiang-I Tsai, Zhanxue Xu, Fuxia Yan, Yingyi Wu, Youmei Xiao, Xiaoyan Liu, Yanping Wu, Sepideh Parvanian, Wangshu Zhu, John E. Eriksson, Dongqing Wang, Haitao Zhu(Correspondence author), Hongbo Chen, Fang Cheng. Exosomal PD-L1 functions as animmunosuppressant to promote wound healing. Journal of Extracellular Vesicles, 2020, (9):1709262.
（9）Kang Wang, Zhengyang Zhang, Hsiang-i Tsai, Yanfang Liu, Jie Gao, Ming Wang, Lian Song, Xiongfeng Cao, Zhanxue Xu, Hongbo Chen, Aihua Gong, Dongqing Wang, Fang Cheng, Haitao Zhu(Correspondence author). Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells. Cell Death & Differentiation,2020.
（10）Jie Gao, Zhengyang Zhang, Yanfang Liu, Zining Zhang, Ming Wang, Aihua Gong, Lin Xia, Xiang Liao, Dongqing Wang, Haitao Zhu(Correspondence author). Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus NutrientDeprived Pancreatic Cancer Cell Ferroptosis Resistance. Oxidative Medicine and Cellular Longevity. 2021, 6629804, https://doi.org/10.1155/2021/6629804.
